Biologie Moléculaire et Bioinformatique - le Moulon

Project leader	Johann Joets (contact)
Project team	Olivier Langella, Pierre Montalent, Guy Decoux, Thierry Balliau, Michel Zivy
Project previous staff members	Thomas Leboucher, Gwenn Houel, Luc Moreau, Luc Negroni, Delphine Vincent, Johan Bordeau, Hélène Denos
Project collaborators	Hélène Ferry-Dumazet, Antoine de Daruvar (CBIB, Bordeaux, France) Céline Lalanne, Christophe Plomion (INRA, BIOGECO, Cestas, France)

PROTICdb is a web-based application mainly designed to store and analyse plant proteome data obtained by two-dimensional polyacrylamide gel electrophoresis (2-D PAGE) and mass spectrometry (MS). The objectives of PROTICdb are twofold: 1/ to store, track and query information related to a proteomic experiment, i.e. from tissue sampling to protein identification via the quantitative measurement of protein accumulation by image analysis, 2/ to integrate information from the user own expertise or other sources into a knowledge base, and support the interpretation of the data (e.g. function, post-translational modification, allelic variant determination...). The insertion of data into the relational database of PROTICdb is achieved either by direct upload of output of widely used image analysis and MS identification or by filling web forms. 2-D PAGE annotated maps can be displayed, queried and compared through a graphical interface. Links to external databases are available. Quantitative data can be easily exported into a tabulated format for statistical analyses. PROTICdb is based on the Oracle or the PostgreSQL DataBase Management System (DBMS).

This new version includes an advanced query builder tool. It is now possible to search for protein, sample, gel, ... according to a large number of criteria. A flash tutorial is provided, describing the main functionalities of this new tool.

PROTICdb demo
Visit the local PROTICdb database (06/20/07 network maintenance, you may experience slow connection)

PROTICdb availability
The PROTICdb package (empty database) is available for free here.

Support
Please contact us at This e-mail address is being protected from spam bots, you need JavaScript enabled to view it (whithout 'nospam' !)

Reference
Ferry-Dumazet H, Houel G, Montalent P, Moreau L, Langella O, Negroni L, Vincent D, Lalanne C, de Daruvar A, Plomion C, Zivy M, Joets J. PROTICdb: a web-based application to store, track, query, and compare plant proteome data. Proteomics. (2005) May;5(8):2069-81